2025 — cTBS and emotional attention

Question

Does real cTBS over the left or right DLPFC alter attentional responses to pleasant/distressing versus neutral stimuli?

Population

91 healthy young adults randomized to real/sham stimulation over the left/right DLPFC.

Finding

Participants receiving real cTBS showed differential response times to emotional versus neutral stimuli; no comparable difference appeared in sham conditions. No meaningful left/right hemisphere difference emerged for pleasant versus distressing images.

Why it matters

This provides additional experimental evidence that the DLPFC can be manipulated to alter a proximal emotional-attention mechanism.

Inference boundary

  • no APD/ASPD population;
  • no APD/ASPD symptom endpoint;
  • no aggression endpoint;
  • no demonstration of durable clinical change.

This node strengthens the mechanism branch but does not close the clinical-treatment inference gate.

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